Chloroform is a colorless, volatile, liquid derivative of trichloromethane with an etherlike odor. View or download the chloroform msds material safety data sheet or sds for 102445 from merck. Formerly used as an inhaled anesthetic during surgery, the primary use of chloroform today is in industry, where it is used as a solvent and in the production of the refrigerant freon. The level of exposure depends upon the dose, duration, and work being done. Chloroform chcl3 is a colorless liquid that quickly evaporates into gas. H341 h373 h411 precautionary statements p260 p280 suspected of causing genetic defects.
Sigmaaldrich 288306 page 1 of 6 sigmaaldrich material safety data sheet version 4. Sigmaaldrich material safety data sheet date printed. The mixture separates into a lower red phenolchloroform, an interphase, and a colorless upper aqueous phase. Suspected of damaging fertility or the unborn child.
In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Beware of vapours accumulating to form explosive concentrations. Sigmaaldrich 3050 spruce street saint louis mo 63103 usa. First aid measures general advice move out of dangerous area. You are welcome to collect inspect test at our premises. The information above is believed to be accurate and represents the best information currently available to us.
Ingestion of chloroform by pregnant laboratory animals has resulted in fetotoxicity but not birth defects, and only at levels causing severe maternal effects. Handling, storage and safety please use this guide in conjunction with this products country specific safety data sheet sds and the safe use conditions as described therein. Chloroform has been shown to be carcinogenic in animals after oral exposure, resulting in an increase in kidney and liver tumors. Chloroform safety data sheet according to federal register vol.
Chloroform was used in the past as an extraction solvent for fats, oils and greases. This can be suppressed by adding ethanol as a stabilizer. Soil, sand, vermiculite for disposal by an approved method. Eu risk assessment c hloroform cas 67663 cover rapporteur f rance esr ri eport draft of june 2007 chloroform casno 67663 einecsno 2006638 risk assessment final report 2007 france rapporteur for the risk evaluation of.
Exposure controlspersonal protection components with workplace control parameters components casno. It can harm the eyes, skin, liver, kidneys, and nervous system. Value control parameters update basis chloroform 67663. Physical and chemical properties molecular formula chcl3. Safety data sheet rochester institute of technology. Safety data sheet northwest missouri state university. Ingestion of chloroform by pregnant laboratory animals has resulted in. Chloroform is suitable for pesticide analysis, environmental and gc analysis. Firstaid measures general advice show this safety data sheet to the doctor in. Sigmaaldrich t0886 page 1 of 7 sigmaaldrich material safety data sheet version 4. Deuterated chloroform is a deuterated compound that is is an isotopologue of chloroform in which the hydrogen atom is replaced with a deuterium. Sigma aldrich sigma material safety data sheet version 5. Safety data sheet according to 29cfr19101200 and ghs rev.
Birth defects have been seen in rats and mice exposed by inhalation of chloroform at concentrations greater than 100 ppm in air. Material safety data sheet isopropanol section 1 chemical product and company identification msds name. India veritas house, 70 mint road, fort, mumbai 400 001. Hplc grade product number 270636 brand aldrich company sigmaaldrich. Toxicological information vapor lc50 inhalation vapor rat 47702 mgm. Show this safety data sheet to the doctor in attendance. Methylidyne trichloride, trichloromethane cas number 67663. May cause damage to organs through prolonged or repeated exposure. It is also used as a precursor to ptfe and refrigerants. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only. Safety data sheet material name methyl chloroform sds id. Ph eur find msds or sds, a coa, data sheets and more information.
Chloroform was traditionally made from acetone and bleaching powder, but is now created from the photochemical reaction of. Stop and contain the spill for salvage or absorb in inert absorbent material e. Advice for firefighters use full protective clothing and selfcontained breathing apparatus. The addition will increase the polarity of the solvent and potentially impact certain applications. However, we make no warranty of merchantibility or any other warranty, express or.
Identification of the substancepreparation and of the companyundertaking product name phenol unid no un1671 synonyms phenol molecular weight 94. Chloroform is a volatile chlorinated organic solvent whose vapors have a narcotic effect. This material may be corrosive to human tissue and chlorine may be liberated. If inhaled if breathed in, move person into fresh air. It is widely employed in high resolution nmr studies due to its high chemical and isotopic purity. Due to its light sensitivity, it may undergo degradation with time. Chloroform d deuterochloroform, cdcl 3, deuterated chloroform, is a standard purity solvent for nmr nuclear magnetic resonance analyses. May cause damage to the liver or kidneys through prolonged or repeated inhalation.
Material safety data sheet or sds for chloroform 102445 from merck for download or viewing in the browser. It is a deuterated compound and a member of chloromethanes. Commonly used as a solvent in proton mnr spectroscopy. Sigmaaldrich offers a number of chloroform products. However, we make no warranty of merchantability or any other warranty, express or implied. Specifications, hplc grade the gr is an emd trademark and indicates this chemical reagent is suitable for use in analytical chemistry and that the product meets or exceeds american chem.
258 1556 824 669 362 1298 121 1067 466 307 521 1321 1610 848 1062 1358 680 44 180 1615 1216 521 89 400 231 1300 1273 593 728 400 161 85 794 589 385 1002 421 1016 911 1083